The Relationship between Obesity, Intraoperative Blood Loss, NLR, and CRP with Perioperative Complications in Colorectal Cancer Surgery
DOI:
https://doi.org/10.24843/JBN.2025.v09.i02.p1Keywords:
Colorectal cancer, Obesity, Intraoperative blood loss, Major perioperative complications.Abstract
Aim: This study examines the relationship between obesity, intraoperative blood loss, and systemic
inflammatory responses (NLR and CRP) concerning perioperative complications in colorectal cancer
surgery. Methods: A retrospective analytical observational study was conducted on 96 patients who
underwent colorectal cancer surgery from January 1 to August 31, 2023. The analysis included obesity
history, intraoperative blood loss, NLR, and CRP levels, using descriptive statistics, Chi-Square tests
for Odds Ratios (OR), and logistic regression for adjusted odds ratios. Results: The study found a
38.5% complication rate in patients with BMI ≥25 kg/m² (OR=35) and a 29.5% rate in those with CRP
>150 mg/L (OR=7). Patients with NLR >3 had a 21.1% complication rate (OR=1.3), while those with
intraoperative blood loss >800 mL faced an 83.3% complication rate (OR=36). Logistic regression
indicated that obesity and CRP are independently associated with major complications. Conclusion:
Obesity, intraoperative blood loss, NLR, and CRP collectively influence major perioperative
complications, with obesity and CRP being the most significant independent factors in colorectal cancer
surgery.
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