WITHDRAWAL SYMPTOMS IN A FEMALE POLYDRUG USER

Abstract

Multiple substance abuse (polydrug use) presents complex clinical challenges, particularly in managing withdrawal symptoms. In Denpasar, Bali, social dynamics and the availability of psychoactive substances increase the risk of dependence among the youth population. This research aims to describe the clinical manifestations and management of withdrawal symptoms in a young adult female with a history of methamphetamine, ecstasy, and cannabis use. This study employs a descriptive qualitative research design. Data were collected through in-depth clinical interviews, physical examinations, and psychiatric observations of a 22-year-old female patient at Badan Narkotika Nasional Provinsi Bali in Denpasar. Data analysis was performed descriptively by comparing clinical findings against DSM-5 diagnostic criteria and current literature regarding multiple substance withdrawal syndromes. The patient exhibited overlapping withdrawal symptoms, including severe irritability, somnolence, increased appetite (methamphetamine/ecstasy effects), as well as anxiety and sleep disturbances (cannabis effects). Secondary depressive symptoms and persistent craving were also observed. Supportive management and symptomatic pharmacological interventions showed significant clinical improvement by the seventh day of treatment, although the risk of relapse remained high due to social environmental factors. Withdrawal symptoms in polydrug users require a comprehensive diagnostic approach. Close monitoring of affective and physical symptoms is crucial during the detoxification phase to prevent further psychiatric complications in young adult patients.