ASSOCIATION BETWEEN CD4 CELL COUNT AND OCULAR SYPHILIS IN HIV-INFECTED POPULATION: A CROSS-SECTIONAL ANALYSIS

Saphira Evani; Ida Ayu Ary Pramita; I Gusti Ayu Made Juliari

Penulis

Saphira Evani Ophthalmology Resident, Ophthalmology Study Program, Faculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali Penulis
Ida Ayu Ary Pramita Ophthalmologist, Department of Ophthalmology, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali Penulis
I Gusti Ayu Made Juliari Ophthalmologist, Department of Ophthalmology, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali Penulis

Kata Kunci:

Ocular syphilis., CD4 cell count., uveitis

Abstrak

Background: Ocular syphilis (OS) often presents with symptoms similar to other eye diseases and can be an initial indicator of HIV infection. CD4 cell count serves as an important marker of immune status in HIV-positive individuals. This study aimed to investigate the relationship between CD4 cell counts and ocular syphilis manifestations in people living with HIV.

Methods: A cross-sectional retrospective review was conducted on medical records of 21 HIV-positive patients diagnosed with OS at the Voluntary Counseling and Testing Clinic of Prof. dr. I.G.N.G. Ngoerah General Hospital between 2018 and 2023. Data collected included demographics, CD4 counts, ocular symptoms, and visual acuity.

Results: Among 21 patients, 18 were male (85.7%) and 3 female (14.3%), with a mean age of 35.8 ± 10.7 years. The most common ocular manifestation was bilateral panuveitis. Statistical analysis revealed no significant association between CD4 cell count and ocular manifestations or visual acuity in this population.

Conclusion: Although no significant link was found between CD4 counts and ocular syphilis features, the frequent coexistence of HIV and syphilis supports routine HIV testing for all syphilis patients. Early detection and management of co-infection remain critical for improving clinical outcomes.

Biografi Penulis

Saphira Evani, Ophthalmology Resident, Ophthalmology Study Program, Faculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali

Ophthalmology Resident, Ophthalmology Study Program, Faculty of Medicine, Udayana University, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali
Ida Ayu Ary Pramita, Ophthalmologist, Department of Ophthalmology, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali

Ophthalmologist, Department of Ophthalmology, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali
I Gusti Ayu Made Juliari, Ophthalmologist, Department of Ophthalmology, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali

Ophthalmologist, Department of Ophthalmology, Prof. Dr. I.G.N.G. Ngoerah General Hospital, Denpasar, Bali